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A distinction should be drawn between general travellers' diarrhoea, and severe diarrhoea.
The former which is more of an annoyance than a major problem, can normally be clocked up to changes in diet, time-zone, irregular eating and general stress.
From a where you will stay to how you will get around.... The art of travel is about the most pretentious way of saying this.
If you have done it before, all this will sound pretty boring and obvious, like someone telling you how to get up and go to college or work.
To quote from a book about climbing Mount Everest, the author stated that the hardest challenge with mountaineering in Nepal is not getting sick in Kathmandu!
Just remember, you may go a year and not have a problem or get ill on your first day in somewhere like Crete or Las Vegas.The bacteria responsible for diarrhoea and related symptoms normally die after 36 hours.If it lasts longer than this, chances are you have nothing serious, but something treatable, for instance giardia (indicated by severe flatulence, stomach cramps and sulphurous belching) which is cured by Flagyl (Metronidazole) - see a pharmacist.The latter is more serious and could be something much nastier.There are literary dozens of different strains of both and it's pointless to cover them here, but most encountered (normally bacterial) aren't too serious.